Managing Director, Chris Allen, says, “Broughton Laboratories success depends on the quality of the individuals within the team, and the recent changes reflect the hard work these individuals have made in assuring that our clients expectations are met day in day out. Despite the tough economic climate we have shown a significant level of growth in the first quarter of 2012. The recent promotions further build on the strong and united foundation of the business and I wish them all success within their new roles”.

In other news, a further two Thermo Fisher Ultimate 3000 UHPLC systems and two Hanson G2 Dissolution Test Stations have been added to the equipment range. These acquisitions again demonstrate our commitment to purchasing new and up to date analytical equipment and our long standing relationships with two of our preferred suppliers.

For a PDF version of this article, please click here

Name
Mike Edwards
Job summary
My main responsibility is to supervise commercial operations of stability services; this includes maintaining our stability storage facility and all stability equipment as well as providing support for the growth of the business.
What do you enjoy about the role?
I love the variety of opportunity that the role provides; no two days are ever the same! I enjoy working within a team of specialists who are all experts in their fields; it is reassuring to know that we can always get the best outcome from any situation. I also enjoy taking ownership for my work, putting in the time and effort and appreciating the results.
Favourite moment so far?
My favourite moment was completing the validation for the stability facility and moving to routine operations.
Top tip?
Always be prepared for the unexpected.

New to the Analytical Services Team:
(Back row left to right)

• Nicole Jackson
• Kerry Malone
• Matthew Stubbs
• Stephen Howarth
• Andrew Kilby

(Front row left to right)

• Kelly Walsh
• Victoria Morris
• Chantelle McNeil

New to the Software Services Team:

• Pauline Cole
• Scott Dunham

We would like to welcome all the new team members and wish them success in their future careers at Broughton Laboratories!

• 40°C/75%RH
• 30°C/75%RH
• 30°C/65%RH
• 25°C/60%RH
• 20°C - 25°C
• 5°C Refrigerator
• -20°C Freezer

Our Stability Operations Supervisor, Michael Edwards said “This exciting new development at Broughton Laboratories uses cutting edge control and monitoring systems to ensure clients receive high quality service and storage with complete peace of mind. Our aim is to provide the highest level of service and integrity to our customers in continuation with the services that Broughton Laboratories provide.”

Broughton Laboratories Stability Service has a dedicated team of professionals who are passionate about all aspects of stability storage and the service they offer. Each team member is an expert in their field, and understands the importance of a quality and reliable service throughout the lifespan of a study. This allows us to present a full range of services tailored to our client’s requirements.

To find out how our stability services could help your business, or to arrange a tour of the facility, please contact support@broughtonlaboratories.co.uk. For a PDF version of this article, please click here

• Meeting up with clients, contacts and friends
  The event is one of the only opportunities for so many people in the industry to gather together. We had a wonderful time catching up with, and sharing a coffee/beer with existing contacts!
• Making new acquaintances
  We met some wonderful new people from around the world and are looking forward to building relationships with them over the coming months.
• Designing the stand
  We all enjoyed designing and building the stand. Help from John Bollen of John Bollen Design was greatly appreciated and marketing materials and stand graphics from The North Space helped to create the right atmosphere on the Broughton Laboratories stand.
• Takeaway Coffee
  Broughton Laboratories were delighted to offer visitors to the stand a freshly brewed coffee in one of our paper cups (made for us by The Paper Cup Company of Clitheroe). The Broughton cups could be seen on various stands around the exhibition! These were a great item to take to the event and we wouldn’t be surprised if a few other exhibitors follow suit at next year’s event.
• Client case studies
  We were delighted to display some of our clients’ products at the event and these proved very popular with passers-by.
  The ‘Intellicig’, an electronic cigarette produced by CN Creative Ltd drew in many visitors to the stand and provided a great talking point.
  A number of products from Trio Healthcare International could also be seen on display and were of much interest to many visitors.
  It was a really good opportunity for Broughton Laboratories to promote some of our clients’ products and to demonstrate how we can help with product development and testing.

To read more about our client case studies, please have look at the attached PDFs.
Intellicig Case Study
Trio Case Study

• Booking a stand for next year’s event
  Feeling like a key part of, alongside our commitment to support the industry and to exhibit at events such as CPhI led to us reserving a stand for next year’s event in Madrid. We will be at stand 10C90 and are already looking forward to catching up with people again.
  If you would like to discuss any aspect of this article with Broughton Laboratories or to find out how we can help your company, please contact support@broughtonlaboratories.co.uk.

For a PDF version of this article, please click here

Combining the selectivity and sensitivity of the Ultimate 3000 PDA detector along with all Ultimate 3000 systems being UHPLC focussed facilitates the rapid separation and identification of the finished product actives. Broughton Laboratories have recently combined this functionality for one of its clients to reduce the analysis time of a finished product by over 50% thus significantly reducing the costs of outsourcing the finished product analysis.
Broughton Laboratories Managing Director Chris Allen says “in the current economic climate businesses need to look at smarter more efficient ways of reducing the cost and time of getting their products to market. The use of PDA detection and UHPLC allows vastly reduced run-times and often the justification to remove classical wet chemistry identification methods, which provides an opportunity to save time and costs which we can pass directly on to our clients”.

Click here to download the full press release

Carried out in the summer, the two day inspection involved the heavy scrutiny of protocols, specifications, calculations, equipment records, workbooks and training records with very positive conclusions made by the visiting inspectors.

The lead FDA Investigator, considered an expert in GMP compliance and the second Investigator, an analytical chemist who focused upon data integrity, was particularly interested in the thoroughness of the company’s current research into dissolution calibration.

Please click here to download the full press release.

With our newest HPLC system installed and up and running, we now offer a wider range of techniques, including fluorescence and diode array detection along with Ultra High Pressure Liquid Chromatography (UHPLC). We can now offer a great deal of variety when it comes to sample analysis.  We continue to source our HPLC systems from Dionex ensuring the highest quality standards are maintained and thus making training in the use these systems a lot more efficient. Our analysts have more time to spend on core business activities, such as further development, analysis and internal efficiency and quality projects. 

Please click here to download the full press release.

Our clients will have the ability to enter sample details into the system on a simple registration page and assign the required analysis.  This sample submission process is quick, easy and ensures accuracy and continuity of data. The information will be immediately available to us ahead of sample arrival facilitating analysis and the prompt return of results.

This service will be completely free of charge and further demonstrates our passion to provide the highest quality analytical services that are excellent value for money.

For further information regarding our GMP laboratory services please get in touch.

The acetonitrile shortage problem arose as the solvent is mainly manufactured as a by-product in acrylonitrile production and in 2008, due to the recession, there was a dramatic downturn in the global demand for this product - acrylonitrile is used to make plastic products including parts used in the automotive industry.  Latest forecasts suggest that the global recession will continue to affect acetonitrile availability in the foreseeable future.

A lot of analytical methods for drug analysis by HPLC use acetonitrile for sample preparation and in mobile phases.  An increase in acetonitrile costs will therefore have a direct increase in the running costs of your laboratory.  More importantly, the availability of acetonitrile could delay the analysis of test results needed for finished product batch release and therefore causing serious problems to your supply chain.

Here at Broughton Laboratories we have a wealth of experience in dealing with these sorts of business challenges.  We can help you reduce your acetonitrile usage by optimising or re-developing your current analytical methods.  We also have significant expertise in test method validation which is required by regulatory authorities following such changes.

Whether you are looking to reduce your acetonitrile usage, reduce your solvent costs in general or simply improve the effectiveness and efficiency of old analytical methods, please contact us for a free, no-obligation method review.

For more information regarding the acetonitrile shortage, please download our acetonitrile shortage factsheet.